JavaScript What is the significance of 64KB in terms of disc IO and is this relevant in JavaScript?

While disk read may be aligned, the OS makes it transparent for the most part; as you mentioned that you're reading sequentially, it doesn't matter what buffer size you're using. There are no relationship between 64 bit and 64KB alignment (I have only heard of 4K align anyway).

You may want to create a buffer of size of power of 2; just for better aligning with memory allocator. JavaScript abstracts most of the memory allocations, so it doesn't necessary improves performance when you have a 64K or 4K buffer (in normal sense, it should be sufficiently big to reduce syscall overhead).

Do the IO in your favorite style, as long as it is buffered. The buffer size doesn't matter too much if it's 4K or 64K (but too small buffer is bad as unbuffered), but whether the IO is buffered or not, matters very much.

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